| Identification | Back Directory | [Name]
S-acetyl-PEG3-alcohol | [CAS]
153870-20-3 | [Synonyms]
AcS-PEG3-OH
S-acetyl-PEG3-OH
S-acetyl-PEG3-alcohol
Ethanethioic acid, S-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl] ester | [Molecular Formula]
C8H16O4S | [MDL Number]
MFCD22574787 | [MOL File]
153870-20-3.mol | [Molecular Weight]
208.28 |
| Hazard Information | Back Directory | [Description]
S-acetyl-PEG3-alcohol is a PEG linker containing a sulfur acetyl group and a hydroxyl group. The sulfur acetyl group can be removed to produce a thiol moiety. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. | [Uses]
S-acetyl-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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