ChemicalBook--->CAS DataBase List--->1334170-01-2

1334170-01-2

1334170-01-2 Structure

1334170-01-2 Structure
IdentificationBack Directory
[Name]

Bis-PEG7-PFP ester
[CAS]

1334170-01-2
[Synonyms]

PFP-PEG7-PFP
PEG7 BIS-PFP ESTER
Bis-PEG7-PFP ester
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,3,4,5,6-pentafluorophenyl) ester
[Molecular Formula]

C30H32F10O11
[MDL Number]

MFCD18916984
[MOL File]

1334170-01-2.mol
[Molecular Weight]

758.55
Hazard InformationBack Directory
[Description]

Bis-PEG7-PFP ester is a PEG linker containing two PFP ester moieties. PFP esters are activated esters which react with primary amines to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
[Uses]

Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
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