| Identification | Back Directory | [Name]
Dehydroandrographolide | [CAS]
134418-28-3 | [Synonyms]
14-(P)
Dehydrographkide
DEHYDROANDROGRAPHOLIDE
Dehydroandrographoline
Dehydroanddrographolide
ANDROGRAPHOLIDE, DEHYDRO-
14-Deoxy-11-dehydroandrographolide
DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE
2(3H)-Furanone,3-[2-[(1S,4aS,5R,6R,8aS)-decahydro-
6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-,(3E)-
(3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone | [Molecular Formula]
C20H28O5 | [MDL Number]
MFCD03093712 | [MOL File]
134418-28-3.mol | [Molecular Weight]
348.43 |
| Chemical Properties | Back Directory | [Melting point ]
205-208oC | [Boiling point ]
508.0±45.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Acetic Acid (Very Slightly), DMSO (Slightly), Ethanol (Very Slightly) | [form ]
Solid | [pka]
14.84±0.70(Predicted) | [color ]
White | [biological source]
plant (Andrographis paniculata) | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChIKey]
YIIRVUDGRKEWBV-GJVBFGQCSA-N | [SMILES]
OC[C@@]([C@H](O)CC1)(C)C([C@]1(C)[C@H]2C/C=C3C=COC\3=O)CCC2=C |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, easily soluble in ethanol and acetone, soluble in chloroform, slightly soluble in benzene, almost insoluble in water, derived from the whole herb of Andrographis paniculata. | [Uses]
Dehydroandrographolide is a natural diterpenoid with activity against HBV (hepatitis B) DNA replication. Hepatoprotective agent. | [Biological Activity]
Dehydroandrographolide possesses activity against hepatitis B virus DNA replication. |
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