| Identification | Back Directory | [Name]
BocNH-PEG10-CH2CH2NH2 | [CAS]
1347704-59-9 | [Synonyms]
NHBoc-PEG10-amine
BocNH-PEG10-CH2CH2NH2 | [Molecular Formula]
C27H56N2O12 | [MDL Number]
MFCD31656920 | [MOL File]
1347704-59-9.mol | [Molecular Weight]
600.74 |
| Chemical Properties | Back Directory | [Boiling point ]
639.2±55.0 °C(Predicted) | [density ]
1.084±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C, sealed storage, away from moisture and light | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
12.23±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
t-Boc-N-amido-PEG10-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
Boc-NH-PEG10-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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