| Identification | Back Directory | [Name]
HO-PEG6-CH2CH2COOH | [CAS]
1347750-85-9 | [Synonyms]
OH-PEG6-COOH
HO-PEG7-acid
Hydroxy-PEG6-acid
HO-PEG6-CH2CH2COOH
Hydroxy-PEG6-propionic acid
α-hydroxy-ω-propionic acid hexaethylene glycol
3-[(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl)oxy]-propanoic acid
Propanoic acid, 3-[(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl)oxy]- | [Molecular Formula]
C15H30O9 | [MDL Number]
MFCD22574804 | [MOL File]
1347750-85-9.mol | [Molecular Weight]
354.39 |
| Chemical Properties | Back Directory | [Boiling point ]
489.6±45.0 °C(Predicted) | [density ]
1.156±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C15H30O9/c16-2-4-20-6-8-22-10-12-24-14-13-23-11-9-21-7-5-19-3-1-15(17)18/h16H,1-14H2,(H,17,18) | [InChIKey]
LGLHJMFNIHYJBM-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CCOCCOCCOCCOCCOCCOCCO |
| Hazard Information | Back Directory | [Uses]
Hydroxy-PEG6-acid is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs)[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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