| Identification | Back Directory | [Name]
Azido-peg4-pfp ester | [CAS]
1353012-00-6 | [Synonyms]
N3-PEG4-PFP
1353012-00-6
N3-PEG4-PFP ESTER
Azido-peg4-pfp ester
Azido-PEG5-PFP ester
N3-PEG4-C2-Pfp ester
perfluorophenyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate | [Molecular Formula]
C17H20F5N3O6 | [MDL Number]
MFCD20926373 | [MOL File]
1353012-00-6.mol | [Molecular Weight]
457.35 |
| Hazard Information | Back Directory | [Description]
Azido-PEG4-PFP ester is a click reagent containing an azide group and a PFP moiety. The azide group enables Click Chemistry. The PFP ester is can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, comparing with NHS ester, PFP ester is more stable.. The hydrophilic PEG spacer adds to the water solubility of this reagent. | [Uses]
N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
Non-cleavable Linker |
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Borenpharm Co., Ltd
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