| Identification | More | [Name]
N-OMEGA-PROPYL-L-ARGININE | [CAS]
137361-05-8 | [Synonyms]
N-PLA
N&OMEGA
Zinc01546170
N-alpha,N&omega
Na-Boc-Nw,Nw'
-dimethyl-N&omega
-PROPYL-L-ARGININE
-bis-Boc-D-arginine
Nω-Propyl-L-Arginine
NW-PROPYL-L-ARGININE
NG-PROPYL-L-ARGININE
N-2-PROPYL-L-ARGININE
N-OMEGA-PROPYL-L-ARGININE
N5-[IMino(propylaMino)Methyl]-
-Hydroxy-L-arginine monoacetate
-Methyl-L-arginine hydrochloride
-Propyl-L-arginine hydrochloride
Nω-Propyl-L-arginine hydrochloride
-Hydroxy-nor-L-Arginine Dihydrochloride
N5-[IMINO(PROPYLAMINO)METHYL]-L-ORNITHINE
L-N5-(1-IMINO(PROPYLAMINO))METHYL-ORNITHINE
-bis-Z-L-arginine N-hydroxysuccinimide ester
-Nitro-D-arginine methyl ester hydrochloride
-Tris-Z-L-arginine N-hydroxysuccinimide ester
L-N5-(1-IMINO-9-PROPYLAMINO-O-METHYL)ORINTHINE
(S)-2-Amino-5-(3-propylguanidino)pentanoic acid
2(S)-2-AMINO-5-(N-PROPYLGUANIDINO)PENTANOIC ACID
-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine
N5-[Imino(propylamino)methyl]-L-ornithinehydrochloride
-(di-tert-butyloxycarbonyl)-L-arginine cyclohexylammonium salt
-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester
-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine-2-chlorotrityl resin
-(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester hydrochloride
-(2,2,4,6,7-Pentamethyldihydro-benzofuran-5-sulfonyl)-L-arginine allyl ester hydrochloride | [Molecular Formula]
C9H20N4O2 | [MDL Number]
MFCD01320455 | [Molecular Weight]
216.28 | [MOL File]
137361-05-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
198-200?C | [storage temp. ]
Desiccate at RT | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
White to off-white solid. | [color ]
White | [Usage]
A highly selective competitive inhibitor and inactivator of all three isoforms of NOS. | [Stability:]
Very Hygroscopic | [CAS DataBase Reference]
137361-05-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Nω-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). Nω-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a Ki value of 57 nM.1 The Ki values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 μM, respectively. Nω-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.1 | [Chemical Properties]
Off-White Solid | [Uses]
A highly selective competitive inhibitor and inactivator of all three isoforms of NOS. | [Uses]
Nω-Propyl-L-Arginine is a neuronal selective nitric oxide synthase inhibitor (1) and a highly selective competitive inhibitor and inactivator of all three isoforms of NOS (2,3). | [Biological Activity]
Highly selective and potent inhibitor of nNOS (K i = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo . | [storage]
room temperature (desiccate) |
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