ChemicalBook--->CAS DataBase List--->1417795-24-4

1417795-24-4

1417795-24-4 Structure

1417795-24-4 Structure
IdentificationBack Directory
[Name]

TNIK-IN-7
[CAS]

1417795-24-4
[Synonyms]

TNIK-IN-7
[Molecular Formula]

C23H22N4O2
[MOL File]

1417795-24-4.mol
[Molecular Weight]

386.45
Chemical PropertiesBack Directory
[Boiling point ]

589.927±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.289±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

5.598±0.10(predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity[1].
[References]

[1] Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. DOI:10.1016/j.bmcl.2012.11.013
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