| Identification | More | [Name]
2,4-Dibromo-1-fluorobenzene | [CAS]
1435-53-6 | [Synonyms]
1,3-DIBROMO-4-FLUOROBENZENE
1-FLUORO-2,4-DIBROMOBENZENE
2,4-DIBROMO-1-FLUOROBENZENE
2,4-DIBROMOFLUOROBENZENE
Benzene, 2,4-dibromo-1-fluoro-
1,3-Dibromo-4-fluorobenzene, tech., 85%
1,3-Dibromo-4-fluorobenzene 98%
1,3-Dibromo-4-fluorobenzene98%
2,4-DIBROMO-1-FLUOROBENZENE: TECH., 90%
1,3-Dibromo-4-fluorobenzene 85-90% | [EINECS(EC#)]
215-860-4 | [Molecular Formula]
C6H3Br2F | [MDL Number]
MFCD00000283 | [Molecular Weight]
253.89 | [MOL File]
1435-53-6.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29036990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
2,4-Dibromo-1-fluorobenzene is used as an intermediate in pharmaceuticals, pesticides, and liquid crystal materials, as well as in the research of regional selective lithiation of halogenated aromatics and the synthesis of novel pyrethroids. | [Synthesis]
The general procedure for synthesizing 2,4-dibromofluorobenzene from 2-fluoro-5-bromobenzoic acid is as follows: in Example 6, bromoisocyanurate was used to induce the bromination reaction of aromatic carboxylic acids. This was done as follows: a mixture of 2-fluoro-5-bromobenzoic acid (1 mmol), bromoisocyanuric acid ester, additives and solvent (10 mL) was stirred under fluorescent room light (FL) or warm white 3W LED (LL) irradiation. Upon completion of the reaction, the reaction mixture is washed with 1 M aqueous Na2SO3, dried over Na2SO4, filtered through a short pad of neutral alumina, and concentrated under vacuum to give crude 2,4-dibromofluorobenzene. The crude product can be purified by silica gel chromatography as required. The experimental results are detailed in Table 5. | [References]
[1] Patent: WO2017/60905, 2017, A1. Location in patent: Paragraph 00139; 00153 |
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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