| Identification | More | [Name]
2-Bromofluorobenzene | [CAS]
1072-85-1 | [Synonyms]
1-BROMO-2-FLUOROBENZENE
1-BROMOFLUOROBENZENE
2-BROMOFLUOROBENZENE
2-FLUOROBROMOBENZENE
O-BROMOFLUOROBENZENE
O-FLUOROBROMOBENZENE
1,2-Fluorobromobenzene
1-bromo-2-fluoro-benzen
1-fluoro-2-bromo-benzen
1-Fluoro-2-bromobenzene
2-Bromfluorbenzen
Benzene, 1-fluoro-2-bromo-
1-Bromo-2-fluorobenzene,98% [2-Bromofluorobenzene]
o-Bromofluorobenzene,99%
Benzene, 1-bromo-2-fluoro-
2-Bromofluorobenzene 99%
2-Bromofluorobenzene99%
2-BROMO-1-FLUORO-BENZENE
O-BROMO-2-FLUOROBENZENE
2-Flurobromobenzene | [EINECS(EC#)]
214-018-3 | [Molecular Formula]
C6H4BrF | [MDL Number]
MFCD00000282 | [Molecular Weight]
175 | [MOL File]
1072-85-1.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID | [Melting point ]
-8°C | [Boiling point ]
78-82 °C50 mm Hg
| [density ]
1.601 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.534(lit.)
| [Fp ]
110 °F
| [storage temp. ]
Flammables area | [solubility ]
0.35g/l | [form ]
Liquid | [color ]
Clear colorless to light yellow | [Specific Gravity]
1.601 | [Water Solubility ]
insoluble | [BRN ]
1071819 | [InChI]
1S/C6H4BrF/c7-5-3-1-2-4-6(5)8/h1-4H | [InChIKey]
IPWBFGUBXWMIPR-UHFFFAOYSA-N | [SMILES]
Fc1ccccc1Br | [CAS DataBase Reference]
1072-85-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1-bromo-2-fluoro-(1072-85-1) | [EPA Substance Registry System]
1072-85-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F,Xn | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [RTECS ]
DA1050000
| [Hazard Note ]
Flammable/Irritant | [TSCA ]
T | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29036990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Flam. Liq. 3 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Sulfur, (2-bromophenolato-κO)pentafluoro-, (OC-6-21)--->Sulfur, (4-bromophenolato-κO)pentafluoro-, (OC-6-21)- (9CI)-->1-Bromo-2,5-difluorobenzene-->4-Bromo-1,2-difluorobenzene-->3-Bromofluorobenzene-->1,3-Dibromobenzene-->1,4-Dibromobenzene-->Cyclohexane, 1,2,3,4,5,6-hexabromo-1-fluoro--->2,4-Dibromo-1-fluorobenzene | [Preparation Products]
1,4-EPOXY-1,4-DIHYDRONAPHTHALENE-->Triphenylene-->2-Bromo-3-fluorobenzoic acid-->Indolo[3,2,1-jk]carbazole-->2-AMINO-2'-FLUOROBENZOPHENONE-->METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID | [Uses]
1-Bromo-2-fluorobenzene is used as a reactant with cyclopenta-1,3-diene to produce 1,4-dihydro-1,4-methano-naphthalene. This reaction will need reagent Mg, and solvent diethyl ether. The reaction time is 3 hours with the temperature of 20°C, | [Application]
2-Bromofluorobenzene is a starting material for coupling reactions; a useful benzyne precursor. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 26, p. 5149, 1961 DOI: 10.1021/jo01070a089 | [Synthesis]
NaOMe (0.5 mmol; 25 wt% MeOH solution) was added to a slurry of arylboronic acid (10 mmol) in acetonitrile (10 mL/g vs. boric acid). One portion of 1,3-dibromo-5,5-dimethylglycolide (11 mmol) was added to the reaction and the mixture was heated to 40 °C. |
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