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143782-20-1

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143782-20-1 Structure

143782-20-1 Structure
IdentificationBack Directory
[Name]

4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile
[CAS]

143782-20-1
[Synonyms]

185807
RU 56279
4-(4,4-DIMETHYL-2,5-DIOXOIMIDAZOLIDIN-1-YL)-2-TRIFLUOROMETHYLBENZONITRILE
2-(trifluoromethyl)-4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)benzonitrile
4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile
Benzonitrile, 4-(4,4-diMethyl-2,5-dioxo-1-iMidazolidinyl)-2-(trifluoroMethyl)-
[Molecular Formula]

C13H10F3N3O2
[MDL Number]

MFCD19689673
[MOL File]

143782-20-1.mol
[Molecular Weight]

297.23
Chemical PropertiesBack Directory
[density ]

1.46±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C(protect from light)
[pka]

7.69±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile is an intermediate in the synthesis of Oxo-MDV 3100 (Oxo-enzalutamide) (O857800), which is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.
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