| Identification | Back Directory | [Name]
Benzyl-PEG4-CH2CO2tBu | [CAS]
1443467-88-6 | [Synonyms]
Benzyl-PEG3-CH2-Boc
Benzyl-PEG4-CH2CO2tBu
3,6,9,12-Tetraoxatridecanoic acid, 13-phenyl-, 1,1-dimethylethyl ester | [Molecular Formula]
C19H30O6 | [MDL Number]
MFCD28122956 | [MOL File]
1443467-88-6.mol | [Molecular Weight]
354.44 |
| Hazard Information | Back Directory | [Description]
Benzyl-PEG4-CH2CO2tBu is a PEG linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
Benzyl-PEG3-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs | [References]
[1] Girardini M, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479. DOI:10.1016/j.bmc.2019.02.048 |
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