| Identification | Back Directory | [Name]
JWH 018 N-propanoic acid metabolite | [CAS]
1451369-32-6 | [Synonyms]
eMolecules ID: 46024603
VCRZMEAJRGIGCT-UHFFFAOYSA-N
JWH 018 N-propanoic acid metabolite
JWH-072 N-propanoic acid metabolite
3-(1-naphthalenylcarbonyl)-1H-indole-1-propanoicacid
1H-Indole-1-propanoic acid, 3-(1-naphthalenylcarbonyl)- | [Molecular Formula]
C22H17NO3 | [MOL File]
1451369-32-6.mol | [Molecular Weight]
343.38 |
| Chemical Properties | Back Directory | [Boiling point ]
612.5±35.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Methanol: 30 mg/ml | [form ]
A crystalline solid | [pka]
4.51±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
JWH 018 is a mildly selective agonist of peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. JWH 018 binds central cannabinoid (CB1) and CB2 receptors with Ki values of 9.0 and 2.94 nM, respectively. JWH 018 is one of several synthetic CBs that have been included in smoking mixtures. JWH 018 N-propanoic acid metabolite is a major metabolite of JWH 018 that is detectable in urine. The biological and toxicological properties of this compound have not been characterized. This analytical reference standard is intended for forensic and research applications only. | [References]
[1] DENNIS P. LOVETT . Structure elucidation and identification of a common metabolite for naphthoylindole-based synthetic cannabinoids using LC-TOF and comparison to a synthetic reference standard[J]. Forensic science international, 2013, 226 1: Pages 81-87. DOI: 10.1016/j.forsciint.2012.12.012 |
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