| Identification | More | [Name]
Glycylglycyl-L-leucine | [CAS]
14857-82-0 | [Synonyms]
GLYCYL-GLYCYL-L-LEUCINE
GLY-GLY-LEU
H-GLY-GLY-LEU-OH
N-(N-Glycylglycyl)-L-leucine
GLYCYL-GLYCY-L-LEUCINE extrapure | [Molecular Formula]
C10H19N3O4 | [MDL Number]
MFCD00067447 | [Molecular Weight]
245.28 | [MOL File]
14857-82-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
195-198 °C (decomp) | [Boiling point ]
573.7±45.0 °C(Predicted) | [density ]
1.199±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
PBS (pH 7.2): Sparingly soluble: 1-10 mg/ml | [form ]
Solid | [pka]
3.35±0.10(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C10H19N3O4/c1-6(2)3-7(10(16)17)13-9(15)5-12-8(14)4-11/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,15)(H,16,17)/t7-/m0/s1 | [InChIKey]
XPJBQTCXPJNIFE-ZETCQYMHSA-N | [SMILES]
C(O)(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CN | [CAS DataBase Reference]
14857-82-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
Gly-gly-leu is an oligopeptide, and also functions as a plant growth regulator. | [Definition]
ChEBI: Gly-Gly-Leu is a tripeptide composed of glycine, glycine and L-leucine residues joined in sequence. It has a role as a metabolite. | [Synthesis]
Glycylglycyl-L-leucine was prepared in 98% yield by hydrogenolysis of the protected tripeptide and crystallization of the product from aqueous ethanol. This matarial had [α]24D -28.4° (c, 2 in water), reported [α]20D -28. l° (c, 2.53 in water), [α]26D -28.0°, and [α]19D -29.9° (c, 2 in water)[1]. | [References]
[1] Beechham A, et al. Residue rotations of L-leucine in the Di-, Tri-, Tetra-, and Penta-peptides of L-leucine and Glycine containing one L-leucyl residue. Australian Journal of Chemistry, 1967; 20: 1983 - 1989. |
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