ChemicalBook--->CAS DataBase List--->1542132-88-6

1542132-88-6

1542132-88-6 Structure

1542132-88-6 Structure
IdentificationBack Directory
[Name]

ZED-1227
[CAS]

1542132-88-6
[Synonyms]

ZED-1227
ZED 1227,ZED1227
2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1H-imidazol-5-yl)carbonyl]amino]-7-oxo-, methyl ester, (2E,6S)-
[Molecular Formula]

C26H36N6O6
[MDL Number]

MFCD30532544
[MOL File]

1542132-88-6.mol
[Molecular Weight]

528.6
Chemical PropertiesBack Directory
[Boiling point ]

916.3±65.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

10.63±0.20(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

(2E,6S)-7-[[1-[2-[(2-Ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1H-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoic Acid Methyl Ester is a derivative of pyridinone which serves as transglutaminase inhibitors.
[in vivo]

ZED-1227 reduces the activity of intestinal TG2 induced by Polyinosinic:Polycytidylic acid (40 mg/kg) to normal control levels and subdues intestinal inflammation in mice[1].
? ZED-1227 (5 mg/kg; i.g.) is able to inhibit TG2 in the small intestinal mucosa[2].

Animal Model:BALB/c mice[2]
Dosage:5 mg/kg
Administration:Oral gavage
Result:Inhibited TG2 in vivo in the small intestinal mucosa.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

ZED-1227(1542132-88-6)1HNMR
1542132-88-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: Shanghai Biolang biotechnology Co.,Ltd  
Tel: 17764003753
Website: www.chemicalbook.com/ShowSupplierProductsList16943/0_EN.htm
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: http://www.chemegen.com
Company Name: Wuhan Dingxintong Pharmaceutical Co. , Ltd.  
Tel: 15871722230
Website: show.guidechem.com/dxt2019/
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Tachizaki Biomedical Research Center  
Tel: 18014399201
Website: http://www.chemlab-tachizaki.com/
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: Shanghai Easy CDMO Co.,Ltd  
Tel: 021-61734564 13854185395;
Website:
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Sichuan Yiyan Pharmaceutical Research  
Tel: 19949968070; 19949968070
Website:
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Website: www.ruidiresearch.com
Company Name: Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd  
Tel: 025-58851090 17714375163
Website: https://www.aikonchem.com/
Company Name: Shanghai Fine Biotech Co.,Ltd  
Tel: 18221172427
Website: www.fine-biotech.com
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Website: www.caymanchem.com
Company Name: Adooq Bioscience LLC  
Tel: 400-025-6535
Website: http://www.adooq.cn
Tags:1542132-88-6 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.