| Identification | Back Directory | [Name]
2,5,8,11,14-pentaoxahexadecan-16-oic acid | [CAS]
16024-66-1 | [Synonyms]
m-PEG5-CH3COOH
CAS_16024-66-1
Einecs 240-163-7
mPEG4-acetic acid
Methyl-PEG4-CH2COOH
2,5,8,11,14-Pentaoxahexadecan-16-sure
3,6,9,12,15-Pentaoxahexadecanoic acid
2,5,8,11,14-pentaoxahexadecan-16-oic acid
2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid | [EINECS(EC#)]
240-163-7 | [Molecular Formula]
C11H22O7 | [MDL Number]
MFCD00021759 | [MOL File]
16024-66-1.mol | [Molecular Weight]
266.288 |
| Chemical Properties | Back Directory | [Boiling point ]
379.6±32.0 °C(Predicted) | [density ]
1.125±0.06 g/cm3(Predicted) | [solubility ]
DMSO : 100 mg/mL (375.53 mM; Need ultrasonic) | [form ]
Liquid | [pka]
3.39±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
m-PEG5-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs | [References]
[1] TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters. |
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