| Identification | More | [Name]
2-Amino-4-methylthiazole | [CAS]
1603-91-4 | [Synonyms]
2-AMINO-4-METHYL-1,3-THIAZOLE 2-AMINO-4-METHYLTHIAZOL 2-AMINO-4-METHYLTHIAZOLE 4-METHYL-2-THIAZOLYLAMINE 4-metyl-2-thiazolamine LABOTEST-BB LT00080644 TIMTEC-BB SBB004307 2-Thiazolamine,4-methyl- 4-Methyl-1,3-thiazol-2-amine 4-Methyl-2-aminothiazole 4-Methyl-2-thiazolamine 4-Methyl-thiazol-2-ylamine 4-methylthiazol-2-ylamine Nomortiroide Normotiroide Thiazole, 2-amino-4-methyl- 2-Amino-4-methylthiazole, 98+% 4-Methylthiazole-2-amine | [EINECS(EC#)]
216-505-6 | [Molecular Formula]
C4H6N2S | [MDL Number]
MFCD00005329 | [Molecular Weight]
114.17 | [MOL File]
1603-91-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
44-47 °C (lit.) | [Boiling point ]
231-232 °C (lit.) | [density ]
1.176 (estimate) | [refractive index ]
1.5000 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Refrigerator | [solubility ]
soluble in Methanol | [form ]
solid | [pka]
5.36±0.10(Predicted) | [color ]
White to Yellow to Green | [Water Solubility ]
soluble | [Sensitive ]
Hygroscopic | [Merck ]
14,450 | [BRN ]
107890 | [InChI]
1S/C4H6N2S/c1-3-2-7-4(5)6-3/h2H,1H3,(H2,5,6) | [InChIKey]
OUQMXTJYCAJLGO-UHFFFAOYSA-N | [SMILES]
Cc1csc(N)n1 | [LogP]
0.840 (est) | [CAS DataBase Reference]
1603-91-4(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Thiazolamine, 4-methyl-(1603-91-4) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H302-H335 | [Precautionary statements ]
P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280g-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . R36/37:Irritating to eyes and respiratory system . R22:Harmful if swallowed. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S39:Wear eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29341000 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
This study developed a series of novel 2-amino-4-methylthiazole analogues for combating Gram-positive bacterial, Gram-negative bacterial, and fungal infections[1]. 2-Amino-4-methylthiazole serves as a corrosion inhibitor for electrogalvanized steel in 0.1 M neutral NaCl solution[2]. | [References]
[1] Omar, A. M., Ihmaid, S., Habib, E.-S. E., Althagfan, S. S., Ahmed, S., Abulkhair, H. S., & Ahmed, H. E. A. (2020). The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase. Bioorganic Chemistry, 99, Article 103781. https://doi.org/10.1016/j.bioorg.2020.103781 [2] Deng, Q., Jeschke, S., Murdoch, B. J., Hirth, S., Eiden, P., Gorges, J. N., Keil, P., Chen, X.-B., & Cole, I. (2022). In-depth insights of inhibitory behaviour of 2-amino-4-methylthiazole towards galvanised steel in neutral NaCl solution. Corrosion Science, 199, Article 110206. https://doi.org/10.1016/j.corsci.2022.110206
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