| Identification | Back Directory | [Name]
DuocarMycin MB | [CAS]
1613286-58-0 | [Synonyms]
CS-1381
DuocarMycin MB
Carbamic acid, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C27H26ClN3O4 | [MDL Number]
MFCD28968742 | [MOL File]
1613286-58-0.mol | [Molecular Weight]
491.97 |
| Chemical Properties | Back Directory | [Boiling point ]
703.0±60.0 °C(Predicted) | [density ]
1.393±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
9.48±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines.
| [Uses]
Duocarmycin MB is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-agent resistant cell lines. | [IC 50]
Duocarmycins | [storage]
Store at -20°C | [References]
[1]. Searcey M. Duocarmycins--natures prodrugs• Curr Pharm Des. 2002;8(15):1375-89. |
|
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
|