| Identification | Back Directory | [Name]
mPEG12-Br | [CAS]
1620461-89-3 | [Synonyms]
mPEG12-Br
m-PEG12-bromide
Br-(CH2CH2O)12-Me
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontane, 37-bromo- | [Molecular Formula]
C25H51BrO12 | [MDL Number]
MFCD31656940 | [MOL File]
1620461-89-3.mol | [Molecular Weight]
623.57 |
| Chemical Properties | Back Directory | [Boiling point ]
595.6±45.0 °C(Predicted) | [density ]
1.174±0.06 g/cm3(Predicted) | [storage temp. ]
Store at Room Tem. | [solubility ]
Soluble in DCM |
| Hazard Information | Back Directory | [Description]
m-PEG12-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
| Company Name: |
T&W GROUP
|
| Tel: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|