| Identification | Back Directory | [Name]
t-butyoxycarboxy-PEG4-phosphonic acid ethyl ester | [CAS]
1623791-77-4 | [Synonyms]
NUN 91774
Boc-PEG4-phosphonic acid ethyl ester
t-butyoxycarboxy-PEG4-phosphonic acid ethyl ester | [Molecular Formula]
C19H39O9P | [MDL Number]
MFCD31654017 | [MOL File]
1623791-77-4.mol | [Molecular Weight]
442.48 |
| Hazard Information | Back Directory | [Description]
t-butyoxycarboxy-PEG4-phosphonic acid ethyl ester contains a t-Boc protecting group and a phosphonic acid ethyl ester moiety. The t-butyl group is removed under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
Boc-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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