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1639972-90-9

1639972-90-9 Structure

1639972-90-9 Structure
IdentificationBack Directory
[Name]

ANT-431
[CAS]

1639972-90-9
[Synonyms]

ANT-431)
ANT431 (ANT 431
ANT431 sodium (ANT 431
5-(pyridine-3-sulfonamido)thiazole-4-carboxylic acid
5-(pyridine-3-sulfonamido)-1,3-thiazole-4-carboxylic acid
4-Thiazolecarboxylic acid, 5-[(3-pyridinylsulfonyl)amino]-
[Molecular Formula]

C9H7N3O4S2
[MOL File]

1639972-90-9.mol
[Molecular Weight]

285.3
Chemical PropertiesBack Directory
[Boiling point ]

555.5±60.0 °C(Predicted)
[density ]

1.708±0.06 g/cm3(Predicted)
[pka]

2.58±0.36(Predicted)
Hazard InformationBack Directory
[Uses]

ANT431 is a metallo-β-lactamase inhibitor that also restores the effectiveness of Meropenem (HY-13678) in a mouse thigh Escherichia coli infection model[1].
[References]

[1] SAR studies leading to the identification of a novel series of metallo-#-lactamase inhibitors for the treatment of carbapenem-resistant Enterobacteriaceae infections that display efficacy in an animal infection model
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