| Identification | Back Directory | [Name]
1H-Indole-3-acetamide, N-[2-(cyclohexylamino)-1-(4-nitrophenyl)-2-oxoethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]- | [CAS]
1676100-30-3 | [Synonyms]
Cyclophilin inhibitor 3
1H-Indole-3-acetamide, N-[2-(cyclohexylamino)-1-(4-nitrophenyl)-2-oxoethyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]- | [Molecular Formula]
C34H38N4O6 | [MOL File]
1676100-30-3.mol | [Molecular Weight]
598.69 |
| Hazard Information | Back Directory | [Uses]
Cyclophilin inhibitor 3 (compound 7c) is a potent cyclophilin A (CypA) inhibitor with an potent anti-HCV activity (EC50 of 4.2 μM)[1]. | [IC 50]
Cyclophilin A | [References]
[1] Xiaoli Li, et al. SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection. Bioorg Med Chem. 2020 Oct 1;28(19):115679. DOI:10.1016/j.bmc.2020.115679 |
|
|