| Identification | Back Directory | [Name]
ZK164015 | [CAS]
177583-70-9 | [Synonyms]
ZK 164015
2-(4-HYDROXYPHENYL)-3-METHYL-1-[10-(PENTYLSULFONYL)DECYL]-1H-INDOL-5-OL | [Molecular Formula]
C30H43NO4S | [MDL Number]
MFCD06798325 | [MOL File]
177583-70-9.mol | [Molecular Weight]
513.73 |
| Chemical Properties | Back Directory | [Boiling point ]
712.4±55.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 25 mM in ethanol and to 100 mM in DMSO | [form ]
Powder | [pka]
10.17±0.15(Predicted) |
| Hazard Information | Back Directory | [Uses]
ZK 164015 is a potent ER silent antagonist. | [Definition]
ChEBI: 2-(4-hydroxyphenyl)-3-methyl-1-(10-pentylsulfonyldecyl)-5-indolol is a phenylindole. | [Biological Activity]
Potent estrogen receptor silent antagonist. Inhibits 17b-estradiol stimulation of luciferase activity (IC 50 = 0.025 mM) and potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC 50 ~ 1 nM). |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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