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1807512-39-5

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1807512-39-5 Structure

1807512-39-5 Structure
IdentificationBack Directory
[Name]

m-PEG5-phosphonic acid
[CAS]

1807512-39-5
[Synonyms]

m-PEG5-phosphonic acid
Phosphonic acid, P-3,6,9,12,15-pentaoxahexadec-1-yl-
[Molecular Formula]

C11H25O8P
[MDL Number]

MFCD28505503
[MOL File]

1807512-39-5.mol
[Molecular Weight]

316.29
Chemical PropertiesBack Directory
[Boiling point ]

453.0±55.0 °C(Predicted)
[density ]

1.211±0.06 g/cm3(Predicted)
[pka]

2.14±0.10(Predicted)
Hazard InformationBack Directory
[Description]

m-PEG5-phosphonic acid ethyl ester is a PEG chain linker. The hydrophilic PEG linkers increase the water solubility of compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains.
[Uses]

m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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