| Identification | Back Directory | [Name]
Fluorescein-PEG3-(N-Boc)-Amine | [CAS]
1807534-77-5 | [Synonyms]
5-FITC-PEG3-NHBoc
Fluorescein-PEG3-NHBoc
Fluorescein-PEG3-(N-Boc)-Amine
5,8,11-Trioxa-2,14-diazapentadecanoic acid, 15-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-15-thioxo-, 1,1-dimethylethyl ester | [Molecular Formula]
C34H39N3O10S | [MDL Number]
MFCD23726634 | [MOL File]
1807534-77-5.mol | [Molecular Weight]
681.75 |
| Hazard Information | Back Directory | [Description]
Fluorescein-PEG3-(N-Boc)-amine is a heterobiofunctional PEG linker containing a fluorescein dye and a Boc-protected amine group, which can be regenerated by mild acidic conditions and then be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. Fluorescein is a common fluorescent tracer (494nm/521nm) for staining cells, tissues, biomarkers or nanoparticles and this reagent can be used to tag biomolecules and nanoparticles. | [Uses]
Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Alfa Chemistry
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1-516-6625404 |
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https://www.alfa-chemistry.com |
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