1807534-77-5

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1807534-77-5 Structure

Identification	Back Directory
[Name] Fluorescein-PEG3-(N-Boc)-Amine
[CAS] 1807534-77-5
[Synonyms] 5-FITC-PEG3-NHBoc Fluorescein-PEG3-NHBoc Fluorescein-PEG3-(N-Boc)-Amine 5,8,11-Trioxa-2,14-diazapentadecanoic acid, 15-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-15-thioxo-, 1,1-dimethylethyl ester
[Molecular Formula] C34H39N3O10S
[MDL Number] MFCD23726634
[MOL File] 1807534-77-5.mol
[Molecular Weight] 681.75

Chemical Properties	Back Directory
[density ] 1.41±0.1 g/cm3(Predicted)
[solubility ] Soluble in DMF, Acetone, Methanol
[pka] 9.33±0.20(Predicted)

Hazard Information	Back Directory
[Description] Fluorescein-PEG3-(N-Boc)-amine is a heterobiofunctional PEG linker containing a fluorescein dye and a Boc-protected amine group, which can be regenerated by mild acidic conditions and then be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. Fluorescein is a common fluorescent tracer (494nm/521nm) for staining cells, tissues, biomarkers or nanoparticles and this reagent can be used to tag biomolecules and nanoparticles.
[Uses] Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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