1810869-23-8

Directory

1810869-23-8 Structure

Identification	Back Directory
[Name] 2-Chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
[CAS] 1810869-23-8
[Synonyms] 2-Chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-chloro-7-(2-deoxy-4-C-ethynyl-β-D-erythro-pentofuranosyl)-
[Molecular Formula] C13H13ClN4O3
[MOL File] 1810869-23-8.mol
[Molecular Weight] 308.72

Chemical Properties	Back Directory
[density ] 1.63±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 12.67±0.60(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] MK-8527 is an orally active HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI) with antiviral activity. MK-8527 has a similar inhibitory mechanism to ISL (HY-104012)[1][2][3][4].
[References] [1] Gillespie SW, et al. Islatravir: evaluation of clinical development for HIV and HBV. Expert Opin Investig Drugs. 2024 Feb;33(2):85-93. DOI:10.1080/13543784.2024.2305130 [2] Liu AY, et al. CROI 2024: Global Epidemiology and Prevention of HIV and Other Sexually Transmitted Diseases. Top Antivir Med. 2024 Jul 17;32(3):447-482. PMID:39142289 [3] Gunaratne SH, et al. CROI 2024: The Challenges of Sustained Viral Suppression, Advanced HIV Disease, and Ending the HIV Epidemic Targets. Top Antivir Med. 2024 Aug 12;32(4):542-567. PMID:39746674 [4] Zhernov YV, et al. Microbicides for Topical HIV Immunoprophylaxis: Current Status and Future Prospects. Pharmaceuticals (Basel). 2024 May 22;17(6):668. DOI:10.3390/ph17060668

1810869-23-8 suppliers list

Company Name:	Nanjing Yikangda Pharmaceutical Technology Co.LTD
Tel:	18118984557; 18118984557
Website:

Company Name:	Taizhou Zhongzhi Biotechnology Co., Ltd
Tel:	13012344321
Website:

Tags:1810869-23-8 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login