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1821214-50-9

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1821214-50-9 Structure

1821214-50-9 Structure
IdentificationBack Directory
[Name]

TT3-LLN
[CAS]

1821214-50-9
[Synonyms]

TT3-LLN
[Molecular Formula]

C90H174N6O3
[MOL File]

1821214-50-9.mol
[Molecular Weight]

1388.42
Chemical PropertiesBack Directory
[solubility ]

Ethanol: Soluble
[form ]

Oil
[color ]

Light yellow to yellow
[InChIKey]

KIOSQLHXJYTPDN-UHFFFAOYSA-N
[SMILES]

C(C1C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=1)(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Uses]

TT3 is an ionizable lipid-like materials for mRNA delivery[1][2].
[References]

[1] Li B, Luo X, Deng B, et al. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo. Nano Lett. 2015;15(12):8099-8107. DOI:10.1021/acs.nanolett.5b03528
[2] Jiang C, Mei M, Li B, et al. A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo. Cell Res. 2017;27(3):440-443. DOI:10.1038/cr.2017.16
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