1821214-50-9

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1821214-50-9 Structure

Chemical Properties	Back Directory
[solubility ] Ethanol: Soluble
[form ] Oil
[color ] Light yellow to yellow
[InChIKey] KIOSQLHXJYTPDN-UHFFFAOYSA-N
[SMILES] C(C1C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=1)(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC

Safety Data	Back Directory
[Symbol(GHS) ] GHS02,GHS07
[Signal word ] Danger
[Hazard statements ] H225-H319
[Precautionary statements ] P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501

Hazard Information	Back Directory
[Uses] TT3 is an ionizable lipid-like materials for mRNA delivery[1][2].
[References] [1] Li B, Luo X, Deng B, et al. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo. Nano Lett. 2015;15(12):8099-8107. DOI:10.1021/acs.nanolett.5b03528 [2] Jiang C, Mei M, Li B, et al. A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo. Cell Res. 2017;27(3):440-443. DOI:10.1038/cr.2017.16

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