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183320-51-6

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183320-51-6 Structure

183320-51-6 Structure
IdentificationBack Directory
[Name]

OSI-420
[CAS]

183320-51-6
[Synonyms]

CP-473420
OSI420 HCl
7-(2&rsquo
OSI-420 USP/EP/BP
DesMethyl Erlotinib
OSI-420 hydrochloride
6-O-Desmethyl Erlotinib 2
OSI-420 (DesMethyl Erlotinib)
Desmethyl Erlotinib (OSI-420)
Desmethyl Erlotinib hydrochloride
O-Desmethylerlotinib hydrochloride
DesMethyl Erlotinib (CP-473420) HCl
6-O-Desmethyl Erlotinib Hydrochloride
O-Desmethylerlotinib hydrochloride salt
OSI-420 (DesMethyl Erlotinib,CP-473420)
Erlotinib O-Desmethyl Metabolite Isomer HCl
Erlotinib O-DesMethyl Metabolite IsoMer (M14) HCl
Erlotinib O-Desmethyl Metabolite Isomer (M14) Hydrochloride
DESMETHYL ERLOTINIB; CP-473420; OSI420; OSI 420; CP473420; CP 473420
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol
OSI420/OSI-420/Desmethyl erlotinib /O-Desmethylerlotinib hydrochloride
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-o
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanolhydrochloride
2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride
2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride
Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride
Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1)
[EINECS(EC#)]

200-258-5
[Molecular Formula]

C21H22ClN3O4
[MDL Number]

MFCD22420811
[MOL File]

183320-51-6.mol
[Molecular Weight]

415.87
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 50 mg/mL (120.23 mM; Need ultrasonic)
[form ]

Powder
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
[target]

EGFR
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

OSI-420(183320-51-6)1HNMR
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