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1862238-01-4

1862238-01-4 Structure

1862238-01-4 Structure
IdentificationBack Directory
[Name]

MZ-242
[CAS]

1862238-01-4
[Synonyms]

MZ-242
Acetamide, 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-[5-[[3-[[1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-2-thiazolyl]-
[Molecular Formula]

C24H27N7O3S2
[MOL File]

1862238-01-4.mol
[Molecular Weight]

525.65
Hazard InformationBack Directory
[Description]

MZ-242 is a potent and selective Sirt2 inhibitor.
[Uses]

Sirt2-IN-2 (Compound 10) is a selective Sirt2 inhibitor with an IC50 of 0.118 μM[1].
[References]

[1] Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin?2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6. DOI:10.1002/anie.201509843
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