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1878-84-8

1878-84-8 Structure

1878-84-8 Structure
IdentificationMore
[Name]

4-HYDROXYPHENOXYACETIC ACID
[CAS]

1878-84-8
[Synonyms]

4-HYDROXYPHENOXYACETIC ACID
(P-HYDROXYPHENOXY)ACETIC ACID
(4-hydroxyphenoxy)-aceticaci
4-Hydroxyphenoxyacetic acid, 98+%
2-(4-Hydroxyphenoxy)acetic acid
[EINECS(EC#)]

217-525-8
[Molecular Formula]

C8H8O4
[MDL Number]

MFCD00014362
[Molecular Weight]

168.15
[MOL File]

1878-84-8.mol
Chemical PropertiesBack Directory
[Appearance]

off-white to beige fine crystalline powder
[Melting point ]

154-157 °C (lit.)
[Boiling point ]

372.6±17.0 °C(Predicted)
[density ]

1.367±0.06 g/cm3(Predicted)
[solubility ]

soluble in Methanol
[form ]

Fine Crystalline Powder
[pka]

3.27±0.10(Predicted)
[color ]

Off-white to beige
[BRN ]

1952779
[LogP]

0.650
[CAS DataBase Reference]

1878-84-8(CAS DataBase Reference)
[EPA Substance Registry System]

Acetic acid, (4-hydroxyphenoxy)- (1878-84-8)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[TSCA ]

Yes
[HS Code ]

29189990
Hazard InformationBack Directory
[Chemical Properties]

off-white to beige fine crystalline powder
[Uses]

2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.
[Definition]

ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.
[General Description]

(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R22(8) hydrogen bonds.
Spectrum DetailBack Directory
[Spectrum Detail]

4-HYDROXYPHENOXYACETIC ACID(1878-84-8)MS
4-HYDROXYPHENOXYACETIC ACID(1878-84-8)1HNMR
4-HYDROXYPHENOXYACETIC ACID(1878-84-8)FT-IR
4-HYDROXYPHENOXYACETIC ACID(1878-84-8)IR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

(4-Hydroxyphenoxy)acetic acid, 98%(1878-84-8)
[Alfa Aesar]

4-Hydroxyphenoxyacetic acid, 98+%(1878-84-8)
[Sigma Aldrich]

1878-84-8(sigmaaldrich)
[TCI AMERICA]

(4-Hydroxyphenoxy)acetic Acid,>98.0%(GC)(1878-84-8)
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