| Identification | More | [Name]
Sodium chlorodifluoroacetate | [CAS]
1895-39-2 | [Synonyms]
CHLORODIFLUOROACETIC ACID, NA
CHLORODIFLUOROACETIC ACID SODIUM
CHLORODIFLUOROACETIC ACID SODIUM SALT
DIFLUOROCHLOROACETIC ACID SODIUM SALT
SODIUM CHLORODIFLUOROACETATE
chlorodifluoro-aceticacisodiumsalt
Sodium chlorodifluoroacetate 97%
Sodiumchlorodifluoroacetate97%
Acetic acid, chlorodifluoro-, sodium salt
Sodium 2-chloro-2,2-difluoroacetate | [EINECS(EC#)]
217-586-0 | [Molecular Formula]
C2ClF2NaO2 | [MDL Number]
MFCD00064771 | [Molecular Weight]
152.46 | [MOL File]
1895-39-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
196-198 °C (lit.) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Soluble in dimethoxyethane, diglyme (0.60 g mL-1), triglyme, dimethyl formamide. | [form ]
Powder | [color ]
White to off-white | [BRN ]
4162363 | [InChI]
InChI=1S/C2HClF2O2.Na.H/c3-2(4,5)1(6)7;;/h(H,6,7);; | [InChIKey]
MRTAVLDNYYEJHK-UHFFFAOYSA-M | [SMILES]
C(F)(F)(Cl)C(=O)O.[NaH] | [CAS DataBase Reference]
1895-39-2(CAS DataBase Reference) | [EPA Substance Registry System]
1895-39-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT, HYGROSCOPIC | [HS Code ]
29159080 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Uses]
It is used as pharmaceutical intermediate. Reactions of aldehydes with triphenylphosphine and sodium chlorodifluoroacetate yield 1,1-difluoro olefins. It is a general reaction and a one step synthesis. | [Application]
Sodium chlorodifluoroacetate is used for generation of difluorocarbene and the synthesis of difluorocyclopropanes and difluoroalkenes. | [Preparation]
Sodium chlorodifluoroacetate is prepared by careful neutralization of 130.5 g (1.0 mol) of chlorodifluoroacetic acid in 300
mL of Et2O with 53 g (0.5 mol) of anhydrous Na2CO3. The Et2O and water are removed under reduced pressure. The salt is
then dried in a vacuum desiccator over P2O5. [1] | [storage]
Sodium chlorodifluoroacetate is an irritant and is hygroscopic. | [References]
1. Herkes, F. E.; Burton, D. J. OSC 1973, 5, 949 |
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