| Identification | Back Directory | [Name]
1,1,1-Trifluoroethyl-PEG4-Aminooxy | [CAS]
1895922-78-7 | [Synonyms]
1,1,1-Trifluoroethyl-PEG4-Aminooxy
Hydroxylamine, O-(14,14,14-trifluoro-3,6,9,12-tetraoxatetradec-1-yl)- | [Molecular Formula]
C10H20F3NO5 | [MDL Number]
MFCD29764348 | [MOL File]
1895922-78-7.mol | [Molecular Weight]
291.26 |
| Hazard Information | Back Directory | [Description]
1,1,1-Trifluoroethyl-PEG4-aminooxy is a fluorine containing PEG molecule. The aminooxy group can be used in bioconjugation and It reacts with an aldehyde to form an oxime bond. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | [Uses]
1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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