| Identification | Back Directory | [Name]
LTI-291 | [CAS]
1919820-28-2 | [Synonyms]
184658
TI-291
CS-2568
LTI-291
LTI291;LTI 291
5,7-dimethyl-N-((1r,4r)-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]- | [Molecular Formula]
C20H30N4O2 | [MOL File]
1919820-28-2.mol | [Molecular Weight]
358.48 |
| Chemical Properties | Back Directory | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml | [form ]
A solid | [pka]
11.03±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Gcase activator 1 is an activator of glucocerebrosidase (Gcase), with activation rates of more than 60% (1 μM) and between 10%-20% (0.1 μM). Gcase activator 1 can be used for Parkinson's disease and endometriosis research[1]. | [storage]
Store at -20°C | [References]
[1] Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1. |
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