| Identification | Back Directory | [Name]
Boc-aminooxy-PEG3-Propargyl | [CAS]
1951439-46-5 | [Synonyms]
Boc-Aminoxy-PEG3-Alkyne
BOC-AMINOXY-PEG3-PROPARGYL
Boc-aminooxy-PEG3-Propargyl
t-Boc-aminooxy-PEG3-propargyl | [Molecular Formula]
C14H25NO6 | [MDL Number]
MFCD28950770 | [MOL File]
1951439-46-5.mol | [Molecular Weight]
303.35 |
| Hazard Information | Back Directory | [Description]
t-Boc-aminooxy-PEG3-propargyl is a click reagent with a propargyl group and t-Boc-aminooxy group. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. T-Boc-aminooxy group can be free up under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC[1]. | [References]
[1] Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. DOI:10.1021/bc400050k |
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