1951439-46-5

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1951439-46-5 Structure

Identification	Back Directory
[Name] Boc-aminooxy-PEG3-Propargyl
[CAS] 1951439-46-5
[Synonyms] Boc-Aminoxy-PEG3-Alkyne BOC-AMINOXY-PEG3-PROPARGYL Boc-aminooxy-PEG3-Propargyl t-Boc-aminooxy-PEG3-propargyl
[Molecular Formula] C14H25NO6
[MDL Number] MFCD28950770
[MOL File] 1951439-46-5.mol
[Molecular Weight] 303.35

Chemical Properties	Back Directory
[density ] 1.078±0.06 g/cm3(Predicted)

Hazard Information	Back Directory
[Description] t-Boc-aminooxy-PEG3-propargyl is a click reagent with a propargyl group and t-Boc-aminooxy group. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. T-Boc-aminooxy group can be free up under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses] N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC[1].
[References] [1] Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. DOI:10.1021/bc400050k

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