| Identification | Back Directory | [Name]
N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt | [CAS]
2055042-59-4 | [Synonyms]
UUN 42594
N-(Amino-PEG3)-N-bis(PEG3-acid) HCl salt | [Molecular Formula]
C26H52N2O13 | [MDL Number]
MFCD30182040 | [MOL File]
2055042-59-4.mol | [Molecular Weight]
600.7 |
| Chemical Properties | Back Directory | [Boiling point ]
702.3±60.0 °C(Predicted) | [density ]
1.166±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF | [pka]
3.97±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
N-(Amino-PEG3)-N-bis(PEG3-acid) is an aqueous soluble PEG reagent, . The amino group is reactive with activated NHS esters to form a amide bond.. The carboxylic acid groups (CO2H)can react with primary amine compound n the presence of activators. | [Uses]
N-(Amino-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|