| Identification | More | [Name]
2,4-Dimethoxybenzylamine | [CAS]
20781-20-8 | [Synonyms]
2,4-DIMETHOXYBENZYLAMINE
2,5-DIMETHOXYBENZYLAMINE
AURORA KA-7637
RARECHEM AL BW 0153
RARECHEM AL BW 0348
(2,4-dimethoxyphenyl)methanamine
[(2,4-Dimethoxyphenyl)methyl]amine
2,4-Dimethoxybenzenemethanamine
2,4-Dimethyloxybenzylamine | [EINECS(EC#)]
672-586-1 | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD00052811 | [Molecular Weight]
167.21 | [MOL File]
20781-20-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Boiling point ]
95 °C0.2 mm Hg(lit.)
| [density ]
1.113 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.549(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Liquid | [pka]
9.39±0.10(Predicted) | [color ]
Clear colorless to slightly yellow | [Sensitive ]
Air Sensitive | [InChI]
InChI=1S/C9H13NO2/c1-11-8-4-3-7(6-10)9(5-8)12-2/h3-5H,6,10H2,1-2H3 | [InChIKey]
QOWBXWFYRXSBAS-UHFFFAOYSA-N | [SMILES]
C1(CN)=CC=C(OC)C=C1OC | [CAS DataBase Reference]
20781-20-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2735 8/PG 3
| [WGK Germany ]
3
| [RTECS ]
DP4430000
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29222990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
2,4-Dimethoxybenzylamine is an amine nucleophile used to investigate the 1,4- reactivity of 5-bromo-2-indene-1-one. It may be used in the following studies:
- As an ammonia equivalent in the concise synthesis of a series of 2,4,5-trisubstituted oxazoles, via a tandem Ugi/Robinson-Gabriel reaction sequence.
- Total synthesis of (-)-muraymycin (MRY) D2 and its epimer, the antibacterial nucleoside natural product.
- Two-step synthesis of amide derivatives of uracil polyoxin C (UPOC) methyl ester using the Ugi reaction.
- Synthesis of N-hydroxythiourea.
- Synthesis of anti-HIV-1 agents.
| [General Description]
2,4-Dimethoxybenzylamine can be preprepared by reduction (NaBH4 , BF3.OEt2, THF) of 2,4-dimethoxybenzonitrile. |
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