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| | 2,4-Dimethoxybenzaldehyde Basic information |
| | 2,4-Dimethoxybenzaldehyde Chemical Properties |
| Melting point | 67-69 °C (lit.) | | Boiling point | 165 °C/10 mmHg (lit.) | | density | 1.1708 (rough estimate) | | refractive index | 1.5260 (estimate) | | Fp | 165°C/10mm | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform | | form | Fine Crystalline Powder | | color | White to slightly brown | | Water Solubility | insoluble | | Sensitive | Air Sensitive | | BRN | 607989 | | InChI | 1S/C9H10O3/c1-11-8-4-3-7(6-10)9(5-8)12-2/h3-6H,1-2H3 | | InChIKey | LWRSYTXEQUUTKW-UHFFFAOYSA-N | | SMILES | COc1ccc(C=O)c(OC)c1 | | LogP | 1.660 (est) | | CAS DataBase Reference | 613-45-6(CAS DataBase Reference) | | NIST Chemistry Reference | Benzaldehyde, 2,4-dimethoxy-(613-45-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-24/25 | | WGK Germany | 3 | | HS Code | 29124900 | | Storage Class | 11 - Combustible Solids |
| | 2,4-Dimethoxybenzaldehyde Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | 2,4-Dimethoxybenzaldehyde is used as a reagent to specifically quantify phlorotannins. It is also used as a component of hair dyes. | | Reactions | 2,4-Dimethoxybenzaldehyde reacts specifically with 1,3-and 1,3,5-substituted phenols (e.g., phlorotannins) to form a colored product.
| | Synthesis Reference(s) | Synthesis, p. 166, 1984 DOI: 10.1055/s-1984-30768 | | Hazard |
2,4-Dimethoxybenzaldehyde causes skin irritation and serious eye irritation, it may cause respiratory irritation.
| | Synthesis | Pyrophosphoryl chloride (2.266 g, 9 mmol) was added dropwise to a stirred mixture of cold (ice-bath) DMF (1.097 g, 15 mmol) and m-dimethoxybenzene (7.5 mmol) to give a thick green syrup. The mixture was heated at 65°C for 15 hours. The mixture was cooled to give a green solid. Dissolve the green solid in water. Alkalize the green solid with 2 M NaOH, leaving a yellow solid. Sublimation of the product (Kugelrohr) (140-150°C, 0.6 mm Hg) gave the title compound 2,4-dimethoxybenzaldehyde.
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| | 2,4-Dimethoxybenzaldehyde Preparation Products And Raw materials |
| Raw materials | 2,6-Dimethoxybenzaldehyde-->1,1-Dichlorodimethyl ether-->1,3-Dimethoxybenzene | | Preparation Products | 7-Hydroxycoumarin-3-carboxylic acid-->2,4-Dimethoxyphenethylamine-->2,4-Dimethoxybenzylamine-->Decanoic acid-->(R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one-->Methyl 2,4-dimethoxybenzoate-->2,4-Dimethoxyphenylacetic acid-->3-Methoxy-2-nitrobenzaldehyde-->2,4-Dimethoxybenzyl alcohol-->2,4-Dimethoxybenzoic acid |
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