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2079945-75-6

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2079945-75-6 Structure

2079945-75-6 Structure

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[Name] 3-Pyridinecarbonitrile, 6-[(1Z)-2-[3-[(1S,5S,6S)-3-amino-5-methyl-1-(4-morpholinylcarbonyl)-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl]-1-fluoroethenyl]-
[CAS] 2079945-75-6
[Synonyms] BACE1-IN-6 3-Pyridinecarbonitrile, 6-[(1Z)-2-[3-[(1S,5S,6S)-3-amino-5-methyl-1-(4-morpholinylcarbonyl)-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl]-1-fluoroethenyl]-
[Molecular Formula] C25H23F2N5O2S
[MOL File] 2079945-75-6.mol
[Molecular Weight] 495.54

Chemical Properties	Back Directory
[Boiling point ] 713.7±70.0 °C(Predicted)
[density ] 1.45±0.1 g/cm3(Predicted)
[pka] 4.94±0.60(Predicted)

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[Uses] BACE1-IN-6 is a BACE1 inhibitor with an IC50 value of 1.5 nM.
[References] [1] Frohn M, et al. The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127240. DOI:10.1016/j.bmcl.2020.127240

2079945-75-6 suppliers list

Company Name:	TargetMol Chemicals Inc.
Telephone:	15002134094
Website:	https://www.targetmol.cn/

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