| Identification | More | [Name]
VALERIC ANHYDRIDE | [CAS]
2082-59-9 | [Synonyms]
N-PENTANOIC ANHYDRIDE
N-VALERIC ANHYDRIDE
PENTANOIC ANHYDRIDE
VALERIC ANHYDRIDE
Pentanoic acid, anhydride
Pentanoicacid,anhydride
pentanoicacidanhydride
VALERIC ANHYDRIDE 98%
Bis(pentanoic)anhydride
Bispentanoic anhydride
Dipentanoic anhydride | [EINECS(EC#)]
218-212-9 | [Molecular Formula]
C10H18O3 | [MDL Number]
MFCD00009477 | [Molecular Weight]
186.25 | [MOL File]
2082-59-9.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellow liquid | [Melting point ]
-56 °C (lit.) | [Boiling point ]
228-230 °C (lit.) | [density ]
0.944 g/mL at 20 °C(lit.)
| [vapor pressure ]
5Pa at 25℃ | [refractive index ]
n20/D 1.421(lit.)
| [Fp ]
214 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Liquid | [color ]
Clear colorless to yellow | [Specific Gravity]
0.945-0.95 (20.00 °C) | [Water Solubility ]
486.3 mg/L (25 °C,est) | [BRN ]
1770130 | [InChI]
1S/C10H18O3/c1-3-5-7-9(11)13-10(12)8-6-4-2/h3-8H2,1-2H3 | [InChIKey]
DUCKXCGALKOSJF-UHFFFAOYSA-N | [SMILES]
CCCCC(=O)OC(=O)CCCC | [LogP]
3.33 at 25℃ | [CAS DataBase Reference]
2082-59-9(CAS DataBase Reference) | [EPA Substance Registry System]
Pentanoic acid, anhydride (2082-59-9) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 3
| [WGK Germany ]
3
| [TSCA ]
TSCA listed | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29159000 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Hazard Information | Back Directory | [Description]
Valeric anhydride(2082-59-9) is an important organic synthetic raw material or intermediate component, often used in industrial or medical fields. It can be used in the preparation of butylphthalide, resin components, lutein esters, analgesics and organic glass.
| [Chemical Properties]
clear colorless to yellow liquid | [Uses]
Valeric Anhydride(2082-59-9) is used in the synthesis of non-imadazole histamine H3-antagonists. Also used in the preparation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
| [Preparation]
Valeric anhydride was obtained by a treatment of the anhydrous sodium valerate by acid chloride of valeric acid[1]. | [Hazard]
Valeric anhydride is a colourless liquid that is corrosive and irritant. Contact may lead to severe eye irritation. Skin contact may cause severe skin burns and may also trigger allergic skin reactions. | [Flammability and Explosibility]
Nonflammable | [References]
[1] T. S. Kotel’nikova. (2009). Kinetics of alcoholysis of valeric anhydride by cyclohexanol in the presence of formic acid. Russian Journal of Applied Chemistry, 82 3, 466–472. https://doi.org/10.1134/S1070427209030227 |
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