| Chemical Properties | Back Directory | [Boiling point ]
975.4±75.0 °C(Predicted) | [density ]
2.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
-0.78±0.70(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy[1]. | [in vivo]
IACS-8803 shows a superior systemic anti-tumor response in the B16 murine model of melanoma[1]. | [References]
[1] Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640. DOI:10.1016/j.bmcl.2019.126640 |
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