| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.33±0.10(predicted) | [color ]
White to off-white | [Sequence]
Ac-Arg-His-Tyr-Pro-Tyr-Trp-Arg |
| Hazard Information | Back Directory | [Uses]
C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo[1]. | [References]
[1] Li XX, et al. Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists. Int Immunopharmacol. 2021 Nov;100:108074. DOI:10.1016/j.intimp.2021.108074 |
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
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