| Identification | More | [Name]
5-Hydroxyindole-2-carboxylic acid | [CAS]
21598-06-1 | [Synonyms]
5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID
5-HYDROXY-2-INDOLECARBOXYLIC ACID
5-HYDROXYINDOLE-2-CARBOXYLIC ACID
5-Hydroxyindole-2-carboxylicacid,97%
5-HO-ICA
5-Hydroxy-2-indolecarboxylic acid 98% | [EINECS(EC#)]
244-468-6 | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD00005615 | [Molecular Weight]
177.16 | [MOL File]
21598-06-1.mol |
| Chemical Properties | Back Directory | [Appearance]
light yellow to beige crystalline powder | [Melting point ]
249 °C (dec.) (lit.) | [Boiling point ]
309.06°C (rough estimate) | [density ]
1.3312 (rough estimate) | [refractive index ]
1.5200 (estimate) | [storage temp. ]
Refrigerator (+4°C) | [solubility ]
chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown | [form ]
Fuming Liquid | [pka]
4.38±0.30(Predicted) | [color ]
Clear colorless to slightly yellow | [BRN ]
153214 | [CAS DataBase Reference]
21598-06-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R21/22:Harmful in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
light yellow to beige crystalline powder | [Uses]
• ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal | [Uses]
5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine. | [Uses]
A competitive antagonist of potentiation by glycine at the N-methyl-D-aspartate receptors that have been linked to neuronal death, assiciated to such afflictions as stroke and epilepsy. | [Definition]
ChEBI: 5-Hydroxyindole-2-carboxylic acid is an indolyl carboxylic acid. | [General Description]
5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Maya High Purity Chemicals
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| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
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www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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