ChemicalBook--->CAS DataBase List--->2183473-14-3

2183473-14-3

2183473-14-3 Structure

2183473-14-3 Structure
IdentificationBack Directory
[Name]

BDP FL-PEG4-amine TFA salt
[CAS]

2183473-14-3
[Synonyms]

BDP FL-PEG4-amine
BDP FL-PEG4-amine TFA salt
[Molecular Formula]

C24H37BF2N4O5
[MDL Number]

MFCD31692221
[MOL File]

2183473-14-3.mol
[Molecular Weight]

510.38
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF, DCM, low solubility in water
Hazard InformationBack Directory
[Description]

BDP FL-PEG4-amine TFA salt is a BDP FL linker containing an amine group and a hydrophilic PEG spacer arm. The amine group makes the compound more reactive toward carboxylic acids, NHS esters and other carbonyl groups. The hydrophilic PEG spacer arm can increase water solubility.
[Uses]

BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs; Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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