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2186700-48-9

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2186700-48-9 Structure

2186700-48-9 Structure

Identification	Back Directory
[Name] Diacylglycerol acyltransferase inhibitor-2
[CAS] 2186700-48-9
[Synonyms] Diacylglycerol acyltransferase inhibitor-2 5-Pyrimidinecarboxamide, 2-[5-[(3-ethoxy-5-fluoro-2-pyridinyl)oxy]-3-pyridinyl]-N-[(3S)-tetrahydro-3-furanyl]-
[Molecular Formula] C21H20FN5O4
[MOL File] 2186700-48-9.mol
[Molecular Weight] 425.41

Chemical Properties	Back Directory
[Boiling point ] 581.602±50.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.404±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 12.586±0.20(predicted)

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[Uses] Diacylglycerol acyltransferase inhibitor-2 (Example 8) is an inhibitor of Diacylglycerol Acyl Transferase 2 (DGAT2) with an IC50 value of 3.7 nM[1].
[References] [1] Markus Boehm, et al. Diacylglycerol Acyl Transferase 2 Inhibitors. US20240140937A1. 2024-05-02.

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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