ChemicalBook--->CAS DataBase List--->2198483-40-6

2198483-40-6

Request For Quotation

Directory

Chemical Properties

Hazard Information

2198483-40-6 Structure

2198483-40-6 Structure

Identification	Back Directory
[Name] NLRP3-IN-29
[CAS] 2198483-40-6
[Synonyms] NLRP3-IN-29
[Molecular Formula] C21H22N2O3S
[MOL File] 2198483-40-6.mol
[Molecular Weight] 382.48

Chemical Properties	Back Directory
[density ] 1.267±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 5.05±0.10(predicted)

Hazard Information	Back Directory
[Uses] NLRP3-IN-29(Compound 5M) is an inhibitor of NLR family pyrin domain containing 3 (NLRP3). NLRP3-IN-29 has the potential for blood-brain barrier permeability and inflammation inhibition both in vivo and in vitro. NLRP3-IN-29 can be used for research on Alzheimer's disease[1].
[References] [1] Kim EY, et al. Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer's disease. Bioorg Med Chem Lett. 2024 Jan 19;99:129622. DOI:10.1016/j.bmcl.2024.129622

2198483-40-6 suppliers list

Company Name:	Shanghai Chaolan Chemical Technology Center
Tel:	021-QQ：65489617 15618227136
Website:	www.atkchemical.com/

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

Tags:2198483-40-6 Related Product Information

2922814-80-8 2997864-57-8