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2997864-57-8

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2997864-57-8 Structure

2997864-57-8 Structure
IdentificationBack Directory
[Name]

NLRP3-IN-27
[CAS]

2997864-57-8
[Synonyms]

NLRP3-IN-27
[Molecular Formula]

C18H16ClN3O3
[MOL File]

2997864-57-8.mol
[Molecular Weight]

357.79
Chemical PropertiesBack Directory
[Boiling point ]

542.2±60.0 °C(predicted)
[density ]

1.30±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

-0.18±0.12(predicted)
Hazard InformationBack Directory
[Uses]

NLRP3-IN-27 is a selective NLRP3 inhibitor with a IC50 value of 0.55 μM. NLRP3-IN-27 can be used in the study of inflammation and immunity[1].
[References]

[1] Xu Y, et al. Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. J Med Chem. 2024 Jan 11;67(1):555-571. DOI:10.1021/acs.jmedchem.3c01782
2997864-57-8 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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