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2226733-37-3

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2226733-37-3 Structure

2226733-37-3 Structure
IdentificationBack Directory
[Name]

Mal-PEG24-NHS ester
[CAS]

2226733-37-3
[Synonyms]

Mal-PEG24-NHS ester
BMPA-PEG24-NHS Ester
Maleimide-PEG24-NHS Ester
4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73-Tetracosaoxa-76-azanonaheptacontanoic acid, 79-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-77-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
[Molecular Formula]

C62H111N3O31
[MDL Number]

MFCD11041160
[MOL File]

2226733-37-3.mol
[Molecular Weight]

1394.55
Chemical PropertiesBack Directory
[density ]

1.23±0.1 g/cm3(Predicted)
[form ]

Oil
[pka]

15.01±0.46(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
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