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223920-67-0

223920-67-0 Structure

223920-67-0 Structure
IdentificationBack Directory
[Name]

D-LUCIFERIN 1-(4,5-DIMETHOXY-2-NITROPHENYL)ETHYL ESTER
[CAS]

223920-67-0
[Synonyms]

DMNPE
DMNPE-CAGED LUCIFERIN
1-(4,5-dimethoxy-2-nitrophenyl)ethylester
D-LUCIFERIN 1-(4,5-DIMETHOXY-2-NITROPHENYL)ETHYL ESTER
4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester, (4S)-
[Molecular Formula]

C21H19N3O7S2
[MDL Number]

MFCD00467661
[MOL File]

223920-67-0.mol
[Molecular Weight]

489.52
Chemical PropertiesBack Directory
[Boiling point ]

708.2±70.0°C at 760 mmHg
[density ]

1.57±0.1 g/cm3
[Appearance]

Yellow powder
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P362+P364
[HS Code ]

2934208090
Hazard InformationBack Directory
[Description]

D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester is an analog of Luciferin, which is cell-permeable. Upon entering the cell, this compound can be hydrolyzed to D-luciferin generating fluorescence.

[Uses]

DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
[References]

[1] Luque-Ortega JR, et al.
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