| Identification | Back Directory | [Name]
Urea, N-(6-chloro-4-cyclopropyl-3-quinolinyl)-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]- | [CAS]
2244109-29-1 | [Synonyms]
MALT1-IN-8
Urea, N-(6-chloro-4-cyclopropyl-3-quinolinyl)-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]- | [Molecular Formula]
C20H15Cl2N7O | [MOL File]
2244109-29-1.mol | [Molecular Weight]
440.29 |
| Hazard Information | Back Directory | [Uses]
MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8)[1]. | [References]
[1] Nathanael S. Gray, et al. Inhibitors of malt1 and uses thereof. WO2018165385A1. |
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