| Identification | Back Directory | [Name]
6H-Cyclopenta[e]pyrazolo[1,5-a]pyrimidine-6-carboxamide, 2-fluoro-7,8-dihydro-8,8-dimethyl-N-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)-3-pyridinyl]-, (6S)- | [CAS]
2812352-99-9 | [Synonyms]
MALT1-IN-11
6H-Cyclopenta[e]pyrazolo[1,5-a]pyrimidine-6-carboxamide, 2-fluoro-7,8-dihydro-8,8-dimethyl-N-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)-3-pyridinyl]-, (6S)- | [Molecular Formula]
C20H16F4N8O | [MOL File]
2812352-99-9.mol | [Molecular Weight]
460.39 |
| Hazard Information | Back Directory | [Uses]
MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1]. | [References]
[1] Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789. |
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